Summary #872

Molecular control of neurotransmitter linked to autism described

news.yale.edu
  • Scientists get closer to understanding how disruptions in the GABA neurotransmitter cause disorders such as epilepsy, schizophrenia and autism.
  • They took a look at KCC2, a transmitter that releases chloride in cells in a process called phosphorylation.
  • That chloride regulates what GABA does, and plays a crucial role in brain development.
  • It turns out that phosphorylation is reversible, so it’s possible to modulate it with drugs for better treatments.

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