Summary #758

Conserved cell types with divergent features in human versus mouse cortex
  • Single-nucleus RNA-sequencing analysis of cell types in the human cortex shows how different it is from mice.
  • Comparison showed a cellular architecture that enables predictions of properties of human cell types.
  • However, extensive differences were found in proportions, laminar distributions, gene expression and morphology.
  • This shows how important it is to study the human brain directly.


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