Summary #478

New study reveals gut segments organized by function, and opportunities for better drug design
  • Research points out that the intestine, in addition to absorbing nutrients from food, performs an immunological function distributed along its length.
  • Each segment of the intestine performs a specific and different immunological activity, specified the study published in the journal Nature.
  • In the first segments of the intestine where most of the nutrients are absorbed, the intestine performs a less offensive immune function against the pathogens agents.
  • However, in the last segments where disease-producing microbes are eliminated, the intestine performs a more intense and aggressive immunology action to protect the organism.
  • The findings of this research may be useful in surgery, in the development of oral vaccines and in the design of therapeutic treatments against gastrointestinal diseases.


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