Summary #1456

Tiny population of neurons may have big role in depression
  • A group of neurons seems to cause depression due to unpredictable, chronic life stress (and not short-term stress, like exams or big life changes).
  • These particular neurons - AgRP - are also involved in appetite, and in maintaining optimal functioning of the whole human organism.
  • This suggests that AgRP neurons could be a target for treating depression.
  • It’s hard to say if these neurons are the starting point of depression, but they definitely play a big role in the process.
  • The study is limited as it was done in mice, but it provides some important clues to the complex process of how depression forms.


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