Summary #1272

Stanford engineers reprogram yeast cells to become microscopic drug factories

news.stanford.edu
  • In an effort to overcome drug shortages, engineers transformed a special strain of yeast to make plant-based drug substitutes from sugars and amino-acids.
  • After 3 years and 34 genetic changes to the yeast’s DNA, the yeast now produces tropane alkaloids, naturally found in coca leaves and other plants around the world.
  • The study author has previously engineered yeast to produce another plan-based drug, and co-founded a startup to license the technology.
  • They expect this to be used in full-scale production in about two years.

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