Summary #1214

Machine learning reveals recipe for building artificial proteins

news.uchicago.edu
  • Using machine learning models to analyze protein information from genome databases, researchers learn how to design artificial proteins with specific functions.
  • The models analyzed data about chorismate mutase proteins, allowing researchers to learn their design and encode it into synthetic genes.
  • The genes were cloned into bacteria which built the proteins—they had the same functions as natural proteins, and they performed them even better than natural.
  • Researchers don’t yet understand how their machine learning models uncovered the design rules of proteins, but it enables them to create any type of proteins they want.
  • Study authors are commercializing the technology, and hope that it will revolutionize fields like energy, environment (car

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