In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoidahajournals.org
- New bioink allows scientists to 3D-print a human heart with - for the first time - cardiac muscles that can pump.
- It’s a huge step towards printing hearts to replace animal models in transplants, it can also be used for testing cardiac medical devices.
- In order to achieve this, study authors had to find a way to achieve the right density of cardiomyocytes, which are notoriously hard to grow.
- They did it by adding pluripotent (=able to grow into different cells) stem cells into the printed structure first, and turning them into cardiomyocytes inside the printed heart.