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Microbiome Study Could Change The Way Doctors Diagnose Depression

inverse.com
  • Analyzing stool samples from 311 people, researchers linked the gut microbiome to clinical depression.
  • They found distinct bacterial compositions in depressed patients compared to healthy patients, and identified the bacteria that was most different.
  • Depressed patients had more Bacteroides species bacteria, linked to increased inflammation, and less Blautia and Eubacterium, which are anti-inflammatory.
  • This provides new insights for doctors diagnosing mental health issues - they should ask about gut health, and analyze poo samples.
  • It also provides new clues for treating mental health disorders - prebiotics, probiotics, and healthier diets can be prescribed to aid treatments.

Gut microbiome link to deadly lung disease

eurekalert.org
  • Researchers find that the gut may be helpful in diagnosing chronic obstructive pulmonary disease (COPD), and it may be a target for treating the disease.
  • The lung microbiome is a contributing factor in COPD, and it turns out that the gut microbiome is also connected to the development of the disease.
  • Comparing stool samples from COPD patients and healthy people, study authors found major differences.
  • This means that stool samples could be used to diagnose COPD, and that treating the gut microbiome could help treat lung disease.
  • More than 3 million people die because of COPD every year.

Age is no barrier to successful weight loss, new study finds

warwick.ac.uk
  • Researchers studied 242 patients (under 60 and over 60 years old) who attended a weight-loss programme, most of them morbidly obese.
  • Results show no differences between age groups, proving that weight loss is as important for older people - even more so - as for younger people.
  • The programme was based on lifestyle-based changes - diet, physical activity and psychological support - and showed similar results regardless of age.
  • People often don’t care about weight loss in older people, and this study shows that it’s a very harmful perspective to adopt.

Human Ageing Reversed In ‘Holy Grail’ Study

independent.co.uk
  • Clinical trial with 35 people over 64 years old shows that oxygen therapy can reverse two key indicators of biological ageing - telomere length, and senescent cells.
  • Telomeres are protective caps at the end of chromosomes, and senescent cells are malfunctioning, old cells.
  • Patients were placed in a pressurised chamber and given pure oxygen for 90 minutes a day, 5 days a week, for 3 months.
  • At the end, telomere length increased by 20% on average, and senescent cells were reduced by 37% - equivalent to a 25 years younger biological-cellular state.
  • The results are incomparable to lifestyle changes / exercise / diets, and researchers say it’s thanks to inducing cell regeneration through hypoxia (oxygen shortage).

Link between Alzheimer's disease and gut microbiota is confirmed

eurekalert.org
  • Proteins produced by specific intestinal bacteria could modify interactions between the immune and nervous systems, triggering Alzheimer’s.
  • The finding adds to years of studying this link, previous studies have shown that Alzheimer’s patients have reduced microbial diversity in the gut.
  • In this study, 89 people between 65-86 had their blood tested for signs of inflammation and proteins produced by intestinal bacteria.
  • Certain bacterial products of intestinal microbiota were indisputably linked to the amount of amyloid plaques (cause of Alzheimer’s) in the brain.
  • This could lead to innovative new treatments for preventing Alzheimer’s.

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